I study trophoblast-derived extracellular vesicles and how their molecular cargo shapes maternal immune tolerance — bridging clinical laboratory science and engineered stem-cell models.
My work profiles the cargo of lineage-specific trophoblast EVs and tests their immunomodulatory function in engineered models of the maternal–fetal interface.
Isolating extracellular vesicles from iPSC-derived trophoblast lineages (TSC, CT, STB, EVT) and mapping how their cargo reprograms NK cells, macrophages, and T-cell responses.
Integrating miRNA-seq and DIA-LC-MS/MS proteomics to resolve lineage-specific vesicle signatures — including C19MC cluster miRNAs linked to immune tolerance.
Building iPSC-derived trophoblast organoid and stem-cell systems to study placentation and vesicle biogenesis under defined, reproducible conditions.
Exploring MSC- and trophoblast-derived vesicles as cell-free immunomodulatory platforms, characterized to MISEV2023 standards.
I came to bioengineering through the clinical lab — and I never stopped asking what cells are trying to say to one another.
I am a PhD candidate in Dr. Zhen Ma's lab at the BioInspired Syracuse Institute for Materials and Living Systems, where my dissertation investigates trophoblast-derived extracellular vesicles and their role in maternal–fetal immune tolerance.
My path began in Iran with a BS in Medical Laboratory Science and an MS in Hematology, grounding me in clinical and hematological science before I moved into stem-cell engineering and vesicle biology. That combination shapes how I work: rigorous at the bench, and always oriented toward translational impact.
My current project is supported by an NSF NRT EmIRGE-Bio Seed Grant, profiling iPSC-derived trophoblast EV cargo through integrated proteomics and transcriptomics.
Four peer-reviewed publications (2019–2022) in hematology and laboratory science, with current dissertation outputs targeting the Journal of Extracellular Vesicles and AAEV 2026.
Whether it's extracellular vesicles, reproductive immunology, or engineered stem-cell models — I'd be glad to hear from you.
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